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  • 标题:CommentaryPoliomyelitis: residual hurdlesto global eradication
  • 作者:Paola Stefanelli ; Gabriele Buttinelli ; Giovanni Rezza
  • 期刊名称:Annali dell'Istituto Superiore di Sanita
  • 印刷版ISSN:0021-2571
  • 出版年度:2016
  • 卷号:52
  • 期号:4
  • 页码:469-471
  • DOI:10.4415/ANN_16_04_01
  • 出版社:Editrice Kurtis Srl
  • 摘要:The global eradication of polio is close to achieving success. However, transmission ofwild poliovirus persists in countries where the disease is endemic, and outbreaks may alsooccur in previously polio-free countries where population immunity is not maintained.To achieve polio eradication, several key actions are required: (1) to detect any poliovirustransmission, (2) to strengthen immunization systems and withdraw all oral poliovaccines from use, (3) to contain polioviruses and certify interruption of transmission,and (4) to sustain ongoing public health programs. In this context, residual hurdles toglobal polio eradication have been identified, from unstable political situation in affectedcountries to population movements from and to endemic areas, and opposition to immunizationstrategies. Global efforts are needed in order to promote routine immunizationcampaigns and large-scale vaccination rounds, which may provide direct protection ofindividuals and minimize virus circulation.
  • 关键词:poliovirus; acute flaccid paralysis; vaccination; eradication
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