摘要:Variola (smallpox) virus is classified as class A of potential biological weapons, due toits microbiological, genetic, antigenic and epidemiological characteristics. The potentialdanger is more real because vaccination against smallpox has stopped since diseaseeradication in 1979. That is why we want to share our unique, rich experience and acquiredknowledge in the fight against this highly contagious and deadly disease duringthe smallpox outbreak in ex-Yugoslavia in 1972. It was the largest postwar outbreakin Europe when there were officially registered 175 ill patients, 35 of them with lethaloutcome. This outbreak was specific by the time of its occurrence, the affected territory,dimensions and some epidemiological characteristics, but also by the well-organized,synchronized and efficient reaction of the competent state services in the fight against it.