摘要:Objectives. We examined whether perceived unfair treatment is associated with health conditions, whether social support moderates this association, and whether such relationships differ by location. Methods. Data were derived from the 1998–1999 Filipino American Community Epidemiological Study, a cross-sectional investigation of 2241 Filipino Americans living in San Francisco and Honolulu. Negative binomial regression was used to examine potential 2-way and 3-way interactions between support, unfair treatment, and city (San Francisco vs Honolulu). Results. Reports of unfair treatment were associated with increased illness after control for education, employment, acculturation, ethnic identity, negative life events, gender, and age. Furthermore, 2-way interactions were found between instrumental support and city, emotional support and city, and unfair treatment and city, and a 3-way interaction was shown between instrumental support, unfair treatment, and city. Conclusions. Local contexts may influence the types of treatment encountered by members of ethnic minority groups, as well as their resources. These factors in turn may have implications for health disparities and well-being Health disparities between population groups may arise when members of minority groups face a greater burden of stressors such as racial discrimination. 1 , 2 Indeed, numerous cross-sectional and longitudinal studies have shown that perceived discrimination may promote illness. 3 – 7 Despite much research, several unresolved questions remain; for example, there is limited knowledge about the factors that may buffer the relationship between discrimination and health and how context may influence experiences of discrimination. We examined the association between perceived discrimination and physical health conditions, assessed social support as a potential moderator of this association, and investigated whether relationships were constant by location.