摘要:Objectives. We investigated vaccine risk perception among reporters of autism to the Vaccine Adverse Event Reporting System (VAERS). Methods. We conducted structured interviews with 124 parents who reported autism and related disorders to VAERS from 1990 to 2001 and compared results with those of a published survey of parents in the general population. Results. Respondents perceived vaccine-preventable diseases as less serious than did other parents. Only 15% of respondents deemed immunization extremely important for children’s health; two thirds had withheld vaccines from their children. Conclusions. Views of parents who believe vaccines injured their children differ significantly from those of the general population regarding the benefits of immunization. Understanding the factors that shape this perspective can improve communication among vaccine providers, policymakers, and parents/patients. Despite scientific evidence that vaccination does not cause autism, 1– 11 many people continue to believe that a causal association exists. Particularly after a case series 12 concerning measles–mumps–rubella vaccine (MMR), autism, and gastrointestinal symptoms received wide publicity, the public became concerned about a possible link. Understanding people’s mental models 13 of autism, that is, their existing understanding and prior beliefs about vaccines and autism, might help to improve communication about vaccines among vaccine providers, policy makers, and parents/patients. To contribute to this understanding, we identified Vaccine Adverse Event Reporting System (VAERS) reports of autism and related disorders, telephoned those VAERS reporters, and conducted structured interviews to characterize their risk perceptions.