摘要：Objectives. We investigated the prevalence and characteristics of HIV-positive women who do not report highly active antiretroviral therapy (HAART) use. Methods. We analyzed HAART use among 1165 HIV-positive participants in the Women’s Interagency HIV Study. Results. Between October 1, 2000, and March 31, 2001, 254 women with clinical indications for HAART reported not using it, 635 reported HAART use, and 276 had no clinical indications. In multivariate analysis, using crack/cocaine/heroin and a history of abuse decreased the likelihood of using HAART, whereas being White increased it. Conclusions. One of 4 women for whom HAART was indicated reported not using HAART. Childhood sexual abuse prevention, more intensive abuse treatment, and continuing drug treatment may enhance HIV disease treatment of women. Women are one of the fastest-growing groups infected with human immunodeficiency virus (HIV) in the United States. 1 When women with HIV use highly active antiretroviral therapy (HAART), dramatic declines in morbidity and mortality have been reported. 2– 5 However, both patient and provider characteristics have been shown to influence HAART use in women. As we have previously shown, African American women, those with a history of injection drug use, and those currently using alcohol and illicit drugs were less likely to report initiating HAART. 6 Additionally, women with high levels of depressive symptoms are less likely to use HAART, whereas those receiving mental health treatment are more likely to report use of HAART. 7 Further, women receiving care from HIV specialists are more likely to receive recommended antiretroviral therapy. 8 As HAART regimens become more varied and convenient, it is important to examine why women who are medically eligible for this therapy remain untreated. We report here on the prevalence and predictors of lack of HAART use in 2000–2001 among medically eligible women enrolled in the Women’s Interagency HIV Study (WIHS), a cohort study of women with and at risk for HIV infection, representative of women with HIV in the United States. 9
