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  • 标题:Evaluation the Response to Treatment of Vitamin D Deficiency in Iranian Overweight/obese Children
  • 作者:Shahsanam Gheibi ; Ahmad Ali Nikibakhsh ; Roghayyeh Goshaderou
  • 期刊名称:International Journal of Pediatrics
  • 印刷版ISSN:2345-5047
  • 电子版ISSN:2345-5055
  • 出版年度:2016
  • 卷号:4
  • 期号:2
  • 页码:1305-1313
  • DOI:10.22038/ijp.2016.6444
  • 语种:English
  • 出版社:Mashhad University of Medical Sciences
  • 其他摘要:Background Recently the prevalence of obesity and its comorbidities has increased in children, in the worldwide. Some evidences show that there is a reverse relation between the serum level of 25-hydroxyvitamin D[25(OH)D] and Body mass index (BMI). The purpose of this study was scrutiny response to treatment vitamin D deficiency in obese/overweight children. Materials and Methods In this cross sectional study 60 children 5 -15 years old with BMI≥85% were entered. After obtaining of informed consent the calcium, phosphorous, alkaline phosphatase, 25(OH) D and parathyroid hormone (PTH) levels were measured after 8 hours of fasting. According to intensity of vitamin D deficiency, intra muscularly vitamin D3, 300,000 to 600,000 unit was prescribed. All parameters were rechecked after 1 month. Data were analyzed with SPSS- 20 software. Results Among total 60 subjects,49 children (81.7%) were overweight and 11 children (18.3%) were obese. Also, all of subjects had vitamin D deficiency. After intervention only 35% got normal level of vitamin D. Mean level of vitamin D in girls were lower than boys. Average level of vitamin D rose significantly after intervention in both overweight and obese groups (P
  • 其他关键词:BMI; Children; Obesity; Treatment; Vitamin D deficiency
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