Monitoring of patients with liver diseases, infectious and non-infectious, is very important both for the sick, to improve their quality of life, but also for the society. Our study was aimed at the way in which the GGT and FA enzymes are used in monitoring liver diseases in people with chronic illnesses (unspecified hepatitis and non-infectious hepatitis) hospitalized in Pitesti County Emergency Hospital, in 2014. Ill people coming from both urban and rural areas are aged between 18 and 97 years old. Increased GGT enzyme activity is found in association with chronic alcoholism, different toxic liver damages, intra hepatic and extrahepatic cholestasis, acute viral hepatitis, pancreatitis, neoplasm disease of the liver and pancreas, myocardial infarction, as well as with diabetes mellitus. The increase in FA (ALP) enzyme activity is prevalent in various hepatic and bone decrease states. The level is also increased in certain diseases of the thyroid gland, intestinal tract and in several bacterial infections. By analyzing how laboratory indices are used in the diagnosis and monitoring of liver diseases, we aim to warn the level would significantly reduce the number of those sick and, at the same time, it would decrease the costs of treatment.