摘要:Since the time of Edward Jenner, vaccines have been scientifically acknowledged to beone of the most cost-effective means for human beings to survive various infectiousdiseases causing enormous morbidity and mortality. In Korea, there had been earlierliterature regarding the concept of vaccination even before Suk-Young Ji introduced thepractice of smallpox vaccination in late 19th century. During the past over 20 years, thenaturally occurring smallpox had been declared eradicated worldwide, and many infectiousdiseases such as diphtheria, tetanus, pertussis, poliomyelitis, measles, mumps,rubella, hepatitis A, hepatitis B, and yellow fever are called vaccine preventable diseases.Now we live in the era of immunization against not only infectious diseases but alsooncologic and/or immunologic diseases. These achievements were built on the remarkabledevelopment of basic sciences which include, but are not limited to, biology,molecular biology, biochemistry, genetics, genetic engineering, immunology, microbiology,and pharmacology.