摘要：Vaccination has proven to be the most cost-effective strategy for controlling a wide variety ofinfectious diseases in humans and animals. For the last decade, veterinary vaccines have beensubstantially developed and demonstrated their effectiveness against many diseases. Nevertheless,new vaccines are greatly demanded to effectively control newly- and re-emergingpathogens in livestock. However, development of veterinary vaccines is a challenging task,in part, due to a variety of pathogens, hosts, and the uniqueness of host-susceptibility to eachpathogen. Therefore, novel concepts of vaccines should be explored to overcome the limitationof conventional vaccines. There have been greatly advanced in the completion of genomic sequencingof pathogens, the application of comparative genomic and transcriptome analysis. Thiswould facilitate to open opportunities up to investigate a new generation of vaccines; recombinantsubunit vaccine, virus-like particle, DNA vaccine, and vector-vehicle vaccine. Currently,such types of vaccines are being actively explored against various livestock diseases, affordingnumerous advantages over conventional vaccines, including ease of production, immunogenicity,safety, and multivalency in a single shot. In this articles, the authors present the current statusof the development of veterinary vaccines at large as well as research activities conducted inKorea.
关键词：Live vaccine; Killed vaccine; Industry animal; Vector vaccine; Development
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