首页    期刊浏览 2024年12月01日 星期日
登录注册

文章基本信息

  • 标题:High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia
  • 作者:Yulia Khabarova ; Valentina Grigoryeva ; Sari Tuomisto
  • 期刊名称:International Journal of Circumpolar Health
  • 印刷版ISSN:1239-9736
  • 电子版ISSN:2242-3982
  • 出版年度:2012
  • 卷号:71
  • 期号:1
  • 页码:17898
  • DOI:10.3402/ijch.v71i0.17898
  • 语种:English
  • 摘要:Objectives The frequency of adult-type hypolactasia (lactase non-persistence) varies widely among different ethnic groups. The cultural historical hypothesis assumes a link between the occurrence of hypolactasia and the distribution of dairy farming. The nomadic Nenets have been reindeer herders for generations and have therefore not consumed any dairy products. The hypotheses here was that the prevalence of lactase non-persistence (−13910 C/C genotype) among Nenets people having four Nenets grandparents is high, while the prevalence among Nenets originating from ethnically mixed families is lower. Study design The material was collected in four typical Nenets settlements in the Nenets Autonomous Okrug in Russia. One-third of the adult Nenets population were invited to answer a questionnaire and to donate buccal samples for genotyping by a doctor from the team of medical professionals who make rounds in this area. The total number of available participants was 177. Methods Genotyping was performed with the AbiPrism system. We used the method of concordance of grandparents’ national origin to ascribe ethnicity. Results The prevalence of adult-type hypolactasia (−13910 C/C) among Nenets who had four Nenets grandparents was found to be 90%. The figures among others reporting three, two and one grandparent of Nenets origin were 72, 60 and 28%, respectively. Conclusion The findings are in accord with the cultural historical hypothesis.
  • 关键词:adult-type hypolactasia ; lactase non-persistence ; cultural historical hypothesis ; nomadic Nenets ; genotyping
Loading...
联系我们|关于我们|网站声明
国家哲学社会科学文献中心版权所有