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  • 标题:Chiral Calcium-Catalyzed Asymmetric Epoxidation Reactions Using Hydrogen Peroxide as the Terminal Oxidant
  • 作者:Yasuhiro Yamashita ; Joseph Alexander Macor ; Seiya Fushimi
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2018
  • 卷号:66
  • 期号:9
  • 页码:847-850
  • DOI:10.1248/cpb.c18-00485
  • 语种:English
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Asymmetric epoxidation reactions of chalcone derivatives catalyzed by chiral calcium complexes using hydrogen peroxide were developed. The epoxidation reactions proceeded smoothly to afford the desired products in good yields with good enantioselectivities. This is the first example of chiral calcium-catalyzed asymmetric epoxidation reactions using hydrogen peroxide as the terminal oxidant.
  • 关键词:chiral calcium catalyst;asymmetric epoxidation;hydrogen peroxide
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