摘要：We analyzed cardiovascular disease mortality risks associated with obesity using participant-level meta-analysis of data from the Black Pooling Project for Black and White individuals. The adjusted relative risks (ARRs) were stronger among White participants than among Black participants for coronary heart disease AAR=1.21 (95% confidence interval [CI]=1.07, 1.36) versus 0.87 (95% CI=0.69, 1.09), respectively, and cardiovascular disease ARR=1.18 (95% CI=1.07, 1.29) versus 0.91 (95% CI=0.77, 1.05), repectively. The results suggest that obesity is an independent risk factor in White people, and additional study of body size and disease progression is necessary in the assessment of racial disparities. Increased body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) has been associated with increased risks for cardiovascular disease. 1 – 4 Likewise, the racial disparities in obesity, cardiovascular disease, and stroke have left Black patients with a particularly heavy disease burden. 5 – 7 However, the disease risks attributed to obesity are inconsistent and less clear for Black individuals than for White individuals. 1 , 3 , 4 , 8 – 22 The association between obesity and cardiovascular disease is limited because of the relative paucity of long-term follow-up outcomes for Black men and women. We examined the association between BMI and coronary heart disease (CHD), stroke, and cardiovascular disease mortality by reviewing data from the Black Pooling Project, which includes more than 450 000 person-years of follow-up.
