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  • 标题:Predictors of Intravenous Immunoglobulin (IVIG) Resistance in Children with Kawasaki Disease in Calabria Region, Italy
  • 作者:Valentina Talarico ; Valentina Talarico ; Sara Rizzo
  • 期刊名称:International Journal of Pediatrics
  • 印刷版ISSN:2345-5047
  • 电子版ISSN:2345-5055
  • 出版年度:2019
  • 卷号:7
  • 期号:2
  • 页码:9027-9036
  • DOI:10.22038/ijp.2018.34895.3074
  • 语种:English
  • 出版社:Mashhad University of Medical Sciences
  • 其他摘要:Background Kawasaki disease (KD) is the second most common childhood vasculitis and one of the main causes of acquired heart disease in children. Recent work focuses on the early diagnostic importance of those risk factors that indicate resistance to intravenous immunoglobulin (IVIG) treatment. The objectives of this study were to identify clinical, laboratory and/or instrumental factors that could be correlated with the risk of resistance to IVIG and the applicability of standard score systems. Materials and Methods We retrospectively reviewed clinical records of 23 children with KD, diagnosed in five consecutive years. They all underwent laboratory and echocardiography investigations and initial treatment with IVIG. Based on the response to IVIG they were divided into two groups: IVIG responders (n=14), and IVIG non-responders (n=9). Results 39% (n= 9) of patients were non-responders. Laboratory exams were overlapping between the two groups except for platelets (p
  • 其他关键词:children; Intravenous Immunoglobulin; Kawasaki disease; Resistance
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