摘要：Background : Myocardial infarction in young age is increasing. Identifying risk factors could be important for health promotion. We studied classic atherosclerotic risk factors in premature myocardial infarction. Methods : In this matched case-control study, which was conducted from 2005 to 2007 in Birjand County, the east of Iran, atherosclerotic risk factors ( hypertension , family history of coronary artery diseases, obesity , diabetes mellitus, dyslipidemia) of 98 patients affected by acute myocardial infarction aged under 50 years were compared with that of 98 healthy neighborhood controls. Results : Mean levels of cholesterol, triglyceride, low-density lipoprotein, as well as systolic blood pressure and body mass index were significantly higher in cases than in controls. There was a positive association between coronary artery disease at younger age and dyslipidemia OR=2.8 [95% CI: 1.5, 5.2], smoking OR=6.4 [95% CI: 3.0, 13.5], systolic hypertension OR=3.1 [95% CI: 1.5, 6.3], family history of coronary artery diseases OR=10.9 [95% CI: 3.2, 37.9] and diabetes OR=2.5 [95% CI: 1.04, 6.2]. Conclusion : Smoking, systolic hypertension and dyslipidemia were the most common risk factors among patients with premature myocardial infarction.
其他摘要：Background : Myocardial infarction in young age is increasing. Identifying risk factors could be important for health promotion. We studied classic atherosclerotic risk factors in premature myocardial infarction. Methods : In this matched case-control study, which was conducted from 2005 to 2007 in Birjand County, the east of Iran, atherosclerotic risk factors ( hypertension , family history of coronary artery diseases, obesity , diabetes mellitus, dyslipidemia) of 98 patients affected by acute myocardial infarction aged under 50 years were compared with that of 98 healthy neighborhood controls. Results : Mean levels of cholesterol, triglyceride, low-density lipoprotein, as well as systolic blood pressure and body mass index were significantly higher in cases than in controls. There was a positive association between coronary artery disease at younger age and dyslipidemia OR=2.8 [95% CI: 1.5, 5.2], smoking OR=6.4 [95% CI: 3.0, 13.5], systolic hypertension OR=3.1 [95% CI: 1.5, 6.3], family history of coronary artery diseases OR=10.9 [95% CI: 3.2, 37.9] and diabetes OR=2.5 [95% CI: 1.04, 6.2]. Conclusion : Smoking, systolic hypertension and dyslipidemia were the most common risk factors among patients with premature myocardial infarction.
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