期刊名称：Revista Brasileira de Medicina de Família e Comunidade
印刷版ISSN：1809-5909
电子版ISSN：2179-7994
出版年度：2017
卷号：12
期号：39
页码：1-13
DOI：10.5712/rbmfc12(39)1553
语种：Spanish
出版社：Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)
摘要：Objective: To analyze the bacterial resistance profile and clinical management of urinary tract infections (UTI) in the city of Divinópolis, Brazil. Methods: This is a cross-sectional descriptive study which data were obtained from the positive urine cultures performed in the first half of 2015 in Municipal Laboratory of Microbiology and from interviews with doctors working in the municipal primary care assistance of Divinópolis. Results: Out of the urocultures evaluated (N=802), 72.8% isolated Escherichia coli , 38.6% of them being resistant to trimethoprim-sulfamethoxazole, 33.0% to norfloxacin, 31.8% to ciprofloxacin and 9.0% to nitrofurantoin. In the total amount of 57 physicians interviewed, 73.5% usually order laboratory test for acute uncomplicated cystitis. The antimicrobials of first choice in the empirical treatment of UTI, according to the interviewed, were norfloxacin (56.1%), trimethoprim-sulfamethoxazole (19.3%), ciprofloxacin (10.5%) and nitrofurantoin (8.8%). Conclusion: The data obtained indicate that the rates of bacterial resistance to quinolones are high in UTI and that the empirical therapy adopted by the majority of interviewees goes against this resistance profile. On the other hand, a low resistance to nitrofurantoin was found, which demonstrates the need to elaborate a local treatment protocol.
关键词：Escherichia coli; Farmacorresistencia Microbiana; Atención Primaria de Salud; Uso Racional de Medicamentos;;Escherichia coli; Resistência Microbiana a Medicamentos ; Atenção Primária de Saúde; Uso Racional de Medicamentos
其他关键词：Escherichia coli; Drug Resistance; Microbial; Primary Health Care; Rational Drug Use
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