摘要：Background: Metabolic syndrome (MetS) is defined as the co-occurrence of risk factors for both type 2 diabetes and cardiovascular disease. This includes abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. MetS is associated with significant morbidity and mortality from cardiovascular events and from all-cause mortality. MetS occurs at a higher rate in patients with serious mental illness compared to the general population. Methods: A retrospective chart review was performed to determine the MetS prevalence and antipsychotic prescribing patterns for patients followed by 2 assertive community treatment teams (ACTTs; n=59). MetS criteria including blood pressure, body mass index, waist circumference, fasting cholesterol, and fasting blood sugar levels were extracted. Additional information including patient demographics, psychiatric diagnosis, and prescription medications were also collected and analyzed. Results: The prevalence of the MetS among ACTT patients was 52.5%. The use of the metabolically favorable antipsychotic aripiprazole (n=10) remains limited in this population. There were no patients in this sample who were prescribed ziprasidone, lurasidone, or asenapine, all of which are associated with limited metabolic side effects. Conclusion: MetS is prevalent among patients with severe and persistent mental illness followed by ACTTs. Despite the high rate of MetS in this patient population, the use of antipsychotics with favorable metabolic profiles remains limited.
关键词：metabolic syndrome; atypical antipsychotics; severe and persistent mental illness
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