摘要:Objective: Association of various self-care activities on glycemic control of people with diabetes (PWD) in Pakistan is yet to be explored. The current study aimed to evaluate the association of various diabetes-related self-care activities with glycated hemoglobin (HbA1c) levels and to examine the predictive relationship of patients’ demographic variables with their self-care activities. Patients and methods: A cross-sectional study was conducted on adult PWD (N=218) who were diagnosed with type 2 diabetes mellitus of at least 1 year duration. Self-care activities were examined by using the Urdu version of Diabetes Self-management Questionnaire. Linear regression analysis was conducted to examine the significant predictors for diabetes-related self-care activities and glycemic control. Results: Mean age of the patients was 50.77±13.3 years. Poor glycemic control (HbA1c ≥7%) was observed in majority of the patients (83%). Linear regression analysis revealed that glucose management (β=-0.44; 95% CI -0.438, -0.209; P <0.001) was the strongest predictor for low levels of patients’ HbA1c, followed by dietary control (β=-0.19; 95% CI -0.248, -0.018; P =0.24) and physical activity (β=-0.17; 95% CI -0.165, -0.023; P =0.010), respectively. Linear regression analysis showed that use of oral hypoglycemic agents only (β=-0.218; 95% CI -0.956, -0.200; P =0.003) and higher education level (β=0.204; 95% CI 0.138, 0.777; P =0.005) were significant predictors for higher scores of patients’ self-care activities. Conclusion: The findings support that PWD having better self-reported self-care activities achieve better glycemic control. Patients’ self-care activities should be monitored on a regular basis, especially for those who are at risk of poor glycemic control.