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  • 标题:Four New Compounds Isolated from the Aerial Part of Belamcanda chinensis (L.) and Their Effect on Vascular Smooth Muscle Cell (VSMC) Proliferation
  • 作者:Do Thi Ha ; Do Thi Ha ; Bui Thi Binh
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2019
  • 卷号:67
  • 期号:1
  • 页码:41-46
  • DOI:10.1248/cpb.c18-00645
  • 语种:English
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Bio-guided fractionation of the 70% ethanol extract of Belamcanda chinensis (L.) DC. revealed four new compounds, including 6″- O -acetylembinin ( 5 ), 3″- O -acetylembinin ( 6 ), irigenin 3′- O -β-glucopyranoside ( 8 ), and 2′-acetyl-1,3- O -diferuloylsucrose ( 9 ), along with five known compounds ( 1 – 4 , 7 ). Their chemical structures were determined using extensive NMR data, mass spectroscopy, and comparison with published literature. Among the isolates, compounds 1 and 4 – 7 achieved good regulation of the growth and proliferation of vascular smooth muscle cells.
  • 关键词:Belamcanda chinensis;Iridaceae;flavonoid glycoside;2′-O-acetyl-1,3-O-diferuloylsucrose;vascular smooth muscle cell (VSMC) proliferation
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