期刊名称：Walailak Journal of Science and Technology (WJST)
印刷版ISSN：2228-835X
出版年度：2016
卷号：15
期号：7
页码：503-514
DOI：10.14456/vol15iss2pp%p
语种：English
出版社：Institute of Research and Development, Walailak University.
摘要：A novel wound dressing surface modification was developed by applying plasma-enhanced chemical vapor deposition (PECVD). The cotton wound gauze dressings were treated by the mixed composition of 10 %NH 3 +He and 10 %NH 3 +C 2 H 2 plasmas followed by immersion in silver sulfadiazine (AgSD) solution. A high functionality and a high surface area can thus be obtained by plasma deposition of C 2 H 2 + NH 3 . We reported the effect of a strong interaction between AgSD and cotton gauze yarn by observing the reactive amorphous carbon layer. It had an ability to slow down the release rate of AgSD compounds into the solution, reported as the UV-visible absorbance of the solution released from the plasma-treated gauze. The results showed that the release rate of AgSD molecules was lower, compared to the untreated gauze. Scanning electron microscopy (SEM) micrographs showed the interaction between AgSD and the cotton fibers of the plasma-treated gauze. In the untreated gauze, no such interaction was found. According to the energy dispersive X-ray spectroscopy (EDS) data, %weight of the Ag compound on the treated gauze was higher than the untreated gauze. A test on the antibacterial effect, using Fluid Thioglycollate Medium (FTM) as the culture media, clearly demonstrated that the plasma treated gauze which was immersed with AgSD, had ability to inhibit bacterial growth.
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