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  • 标题:A terapia nutricional na dislipidemia de adolescentes com HIV/AIDS em uso de terapia antirretroviral: um ensaio clínico randomizado
  • 作者:Caroline Barbosa Schmitz ; Carmem Lucia Oliveira da Silva ; Daniéla Oliveira Magro
  • 期刊名称:Adolescência e Saúde
  • 印刷版ISSN:2177-5281
  • 电子版ISSN:1679-9941
  • 出版年度:2018
  • 卷号:15
  • 期号:3
  • 页码:89-100
  • 出版社:Official Scientific Journal of the Adolescent Health Care Center (NESA)/ Rio de Janeiro State University/UERJ
  • 摘要:OBJETIVO: Avaliar a terapia nutricional na dislipidemia de adolescentes com HIV/AIDS em uso de Terapia Antirretroviral (TARV). MÉTODOS: 20 adolescentes participaram do estudo, sendo que 11 eram do sexo feminino. Desses, 10 foram selecionados randomicamente para o grupo de intervenção nutricional, que recebeu acompanhamento nutricional por 12 semanas, e 10 para o grupo de controle com consultas médicas de rotina. O perfil lipídico e o recordatório de 24 horas foram coletados no período basal e ao fim do estudo para ambos os grupos. RESULTADOS: Os níveis séricos de colesterol e triglicerídeos foram reduzidos de 282 ± 69 para 246 ± 67 mg/dL (p = 0,001) e de 137 ± 67 para 104 ± 39 mg dL (p = 0,001), respectivamente, por intervenção nutricional, enquanto no grupo controle, ambos colesterol e triglicerídeos aumentaram (de 287 ± 72 para 307 ± 76 mg/dL, p = 0,047 e 135 ± 70 para 177 ± 81mg/dL, p = 0,001, respectivamente). CONCLUSÃO: A terapia nutricional reduziu os níveis de colesterol total e triglicerídeos não permitindo a piora da dislipidemia nestes pacientes.
  • 其他摘要:OBJECTIVE: Evaluates the nutritional therapyon the lipid profile of HIV-infected adolescents using Highly active antiretroviral therapy (HAART) and with dyslipidemia. METHODS: 20 adolescents participated in the study, 11 were female. Of which 10 were randomly selected for the nutritional intervention group, which received nutritional counseling for 12 weeks, and 10 for the control group who received routine follow-up. Lipid profile and 24-hour dietary recall were obtained before and after the intervention for both groups. Data were analyzed by intention to treat using mixed models. RESULTS: Serum cholesterol levels and triglycerides were reduced from 282 ± 69 to 246 ± 67 mg/dL (p=0.001) and from 137 ± 67 to 104 ± 39 mg/dL (p=0.001) respectively, by nutritional intervention, whereas in the control group both cholesterol and triglycerides increased (from 287 ± 72 for 307 ± 76 mg/dL, p=0.047, and 135 ± 70 to 177 ± 81 mg/dL, p=0.001, respectively). CONCLUSION: Among adolescents with HIV/AIDS and dyslipidemia using HAART, nutritional therapy was effective in reducing serum cholesterol, triglyceride levels and BMI.
  • 关键词:HIV; Síndrome de Imunodeficiência Adquirida; dislipidemias; adolescente; terapia nutricional.
  • 其他关键词:HIV; Acquired Immunodeficiency Syndrome; dyslipidemias; adolescent; nutrition therapy.
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