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  • 标题:Effect of Sarcopenia on Postoperative Mortality in Osteoporotic Hip Fracture Patients
  • 作者:Kim, You Keun ; Yi, Seung Rim ; Lee, Ye Hyun
  • 期刊名称:Journal of Bone Metabolism
  • 印刷版ISSN:2287-6375
  • 出版年度:2018
  • 卷号:25
  • 期号:4
  • 页码:227-233
  • DOI:10.11005/jbm.2018.25.4.227
  • 语种:English
  • 出版社:The Korean Society for Bone and Mineral Research
  • 摘要:Background

    Few studies have investigated the effects of sarcopenia on postoperative outcomes including mortality rates following surgery for osteoporotic hip fractures. The purpose of the present study was to determine the prevalence of sarcopenia and the relationship between sarcopenia and 1- and 5-year mortality rates in a consecutive series of patients with osteoporotic hip fractures.

    Methods

    Among patients who underwent hip surgery for osteoporotic hip fractures, this study included 91 patients subjected to abdominal computed tomography within 1 year of hip surgery. We defined sarcopenia using sex-specific cut-off points for the skeletal muscle index at the level of the third lumbar vertebra. All patients were divided into 2 groups according to the presence or absence of sarcopenia and the 1- and 5-year mortality rates were compared. To confirm factors affecting mortality in addition to sarcopenia, we examined patient age, sex, American Society of Anesthesiologists grade, location of fracture, type of surgery, and bone mineral density.

    Results

    The 1- and 5-year mortality rates were 20.9% and 67.2%, respectively. Among the 45 patients with sarcopenia, the 1- and 5-year mortality rates were 22.2% and 82.7%, respectively. Of the 46 patients without sarcopenia, the 1- and 5-year mortality rates were 19.6% and 52.7%, respectively. Results of the Kaplan-Meier analysis showed that sarcopenia did not affect the 1-year mortality rate ( P =0.793), but had a significant effect on the 5-year mortality rate ( P =0.028). Both perioperative sarcopenia ( P =0.018) and osteoporosis ( P =0.000) affected the 5-year mortality rate.

    Conclusions

    Sarcopenia increases the risk of 5-year mortality in patients with osteoporotic hip fractures.

  • 关键词:Hip fractures; Mortality; Osteoporotic Fractures; Sarcopenia
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