摘要:With the rapid development of online shopping in recent years, logistics distribution has received much attention from enterprises and online consumers. Logistics distribution involves many factors and complex processes; conventional qualitative methods are unable to provide an effective analysis. Thus, this paper sets a framework to solve the above problem. A case study of an E-commerce enterprise in Shanghai on logistics distribution is proposed to discretize the whole process and minimize the total costs. Then the AnyLogic software is used to simulate and optimize the system from three aspects, including routes selection, warehouses quantity, and warehouses layout. Finally, this paper analyzes the simulation results, which would provide some valuable references for practical logistics.