期刊名称：Journal of Applied Sciences and Environmental Management
印刷版ISSN：1119-8362
出版年度：2018
卷号：22
期号：9
页码：1457-1460
出版社：Department of Pure & Industrial Chemistry, University of Port Harcourt
其他摘要：Traditional healers have successfully used several species of the genus Ficus to cure several ailments such as; diarrhea, dysentery, cuts, wounds, mumps, cholera, and jaundice. Ficus natalensis being of the same genus was screened for the presence of phytochemicals and antimicrobial effects. Phytochemical investigation of crude extracts of F. natalensis showed the presence of alkaloids, flavonoids, carbohydrates, saponins, tannins, glycosides, steroids, triterpenes and anthraquinones. The crude hexane, ethylacetate and methanol fractions had inhibitory effects on Staphylococcus aureus, Streptococcus pyrogenes, Escherichia coli, Candida krusei , and Candida tropicalis . Minimum bactericidal/fungicidal concentrations (MBC)/(MFC) and Minimum inhibition concentration (MIC) were carried out on the extracts using the two fold serial dilution method at concentrations of 20 mg/mL, 10 mg/mL, 5 mg/mL, 2.5 mg/mL and 0.63 mg/mL but the crude extracts did not show inhibitory effect on Methicillin resistant Staphylococcusaureus, Shigeiladysenteriae, Vancomycin resistant enterococci, and Campylobacter jejuni .The result in this work agrees with the ethno-medicinal claim on this specie of the genus.
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