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  • 标题:In Vivo Cytotoxicity Induced by 60 Hz Electromagnetic Fields under a High-Voltage Substation Environment
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  • 作者:Heredia-Rojas, J. Antonio ; De la Fuente, Abraham Octavio Rodríguez ; Gomez-Flores, Ricardo
  • 期刊名称:Sustainability
  • 印刷版ISSN:2071-1050
  • 出版年度:2018
  • 卷号:10
  • 期号:8
  • 页码:1-9
  • 出版社:MDPI, Open Access Journal
  • 摘要:Living beings permanently receive electromagnetic radiation, particularly from extremely low-frequency electromagnetic fields (ELF-EMFs), which may cause adverse health effects. In this work, we studied the in vivo cytotoxic effects of exposing BALB/c mice to 60 Hz and 8.8 µT EMFs during 72 h and 240 h in a switchyard area, using animals exposed to 60 Hz and 2.0 mT EMFs or treated with 5 mg/kg mitomycin C (MMC) as positive controls. Micronucleus (MN) frequency and male germ cell analyses were used as cytological endpoints. ELF-EMF exposure was observed to significantly ( p < 0.05) increase MN frequency at all conditions tested, with the 2 mT/72 h treatment causing the highest response, as compared with untreated control. In addition, increased sperm counts were observed after switchyard area ELF-EMF exposure, as compared with untreated control. In contrast, low sperm counts were obtained for 72 h/2.0 mT-exposed animals and for MMC-treated mice ( p < 0.05), without altering male germ cell morphological characteristics.
  • 关键词:electromagnetic fields; cytotoxicity; micronuclei; sperm abnormalities
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