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  • 标题:Ag(I) and Au(III) Mercaptobenzothiazole complexes induced apoptotic cell death
  • 本地全文:下载
  • 作者:Jositta Sherine ; Arun Upadhyay ; Amit Mishra
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2019
  • 卷号:9
  • 期号:1
  • 页码:1-10
  • DOI:10.1038/s41598-018-36801-6
  • 出版社:Springer Nature
  • 摘要:HNMR, ICP - MS and electrochemical studies of the complexes were carried out. The TUNEL assay studies of Ag(I)MBT and Au(III)MBT complexes on A549 cell line indicated induced apoptosis in the cells. TUNEL assay showed 60% cell viability for Ag(I)MBT whereas 80% for Au(III)MBT. Thus Ag(I)MBT can induce cell apoptosis in cells at a higher rate than Au(III)MBT. Therefore these complexes studied here can be a viable option as anti - proliferating agent.
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