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文章基本信息

  • 标题:Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD
  • 本地全文:下载
  • 作者:Zoljargal Baatarkhuu ; Philippe Chaignon ; Franck Borel
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:17892
  • DOI:10.1038/s41598-018-35586-y
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:shows the highest inhibitory activity when compared to known inhibitors of E. coli YgbP/IspD. The mechanism of this enzyme was also studied by steady-state kinetic analysis and it was found that the substrates add to the enzyme in sequential manner.
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