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  • 标题:Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet
  • 本地全文:下载
  • 作者:George D. Mcilroy ; Sharon E. Mitchell ; Weiping Han
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:17863
  • DOI:10.1038/s41598-018-36078-9
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:mice are maintained at thermoneutrality and fed a high-fat diet do subtle alterations to metabolic homeostasis manifest. This is despite a striking inability to expand adipose mass. Our findings provide further evidence that loss of Bscl2 in non-adipose tissues may contribute to the severity of metabolic dysfunction in this condition.
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