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  • 标题:Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays
  • 本地全文:下载
  • 作者:Jonathan C. J. Wei ; Isha N. Haridass ; Michael L. Crichton
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:17759
  • DOI:10.1038/s41598-018-36009-8
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:. In breaching the stratum corneum (SC) and dermal-epidermal junction barriers, we have demonstrated practical application, delivery and targeting of macromolecules to both epidermal and dermal antigen presenting cells, providing a sound knowledge base for future development of skin-targeting clinical technologies in humans.
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