文章基本信息
- 标题:An accurate TMT-based approach to quantify and model lysine susceptibility to conjugation via N-hydroxysuccinimide esters in a monoclonal antibody
- 本地全文:下载
- 作者:Jennifer J. Hill ; Tammy-Lynn Tremblay ; Christopher R. Corbeil 等
- 期刊名称:Scientific Reports
- 电子版ISSN:2045-2322
- 出版年度:2018
- 卷号:8
- 期号:1
- 页码:17680
- DOI:10.1038/s41598-018-35924-0
- 语种:English
- 出版社:Springer Nature
- 摘要:= 0.76). This predictive model will enable improved engineering of antibodies for optimal labeling with fluorophores, toxins, or crosslinkers.