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文章基本信息

  • 标题:Mavoglurant in Fragile X Syndrome: Results of two open-label, extension trials in adults and adolescents
  • 本地全文:下载
  • 作者:Randi Hagerman ; Sebastien Jacquemont ; Elizabeth Berry-Kravis
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:16970
  • DOI:10.1038/s41598-018-34978-4
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:scale were observed, which were numerically superior to those seen in the placebo arm of the core studies. These two extension studies confirm the long-term safety of mavoglurant in FXS, but further investigations are required to determine whether and under which conditions the significant preclinical results obtained with mGluR5 inhibition can translate to humans.
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