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  • 标题:Obesity-induced pancreatopathy in rats is reversible after bariatric surgery
  • 本地全文:下载
  • 作者:Vinciane Rebours ; Philippe Garteiser ; Lara Ribeiro-Parenti
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:16295
  • DOI:10.1038/s41598-018-34515-3
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:rats. MR image quantifications revealed increased elasticity, fat fraction, and R2 and a decreased elasticity wave dispersion coefficient in the high fat groups that reversed after surgery. MRI parameters were in strong correlation with respective histological counterparts. In conclusion, obese rats develop pancreatic inflammatory lesions with acinar-ductal metaplasia in acinar location and the endocrine-exocrine interface. These changes can be prevented by bariatric surgery. Quantitative MR imaging is accurate in identifying early pancreatic lesions.
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