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  • 标题:The Cell Activation Phenomena in the Cold Atmospheric Plasma Cancer Treatment
  • 本地全文:下载
  • 作者:Dayun Yan ; Wenjun Xu ; Xiaoliang Yao
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:15418
  • DOI:10.1038/s41598-018-33914-w
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:. The cytotoxicity of CAP treatment is still dependent on the CAP-originated reactive species. The activation state of cancer cells will not cause noticeable cytotoxicity. This activation is an instantaneous process, started even just 2 s after the CAP treatment begins. The noticeable activation on the cancer cells starts 10-20 s during the CAP treatment. In contrast, the de-sensitization of activation takes 5 hours after the CAP treatment. The CAP-based cell activation explains the mechanism by which direct CAP treatment causes a much stronger cytotoxicity over the cancer cells compared with an indirect CAP treatment do, which is a key to understand what the effect of CAP on cancer cells.
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