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  • 标题:Parasternal intercostal muscle ultrasound in chronic obstructive pulmonary disease correlates with spirometric severity
  • 本地全文:下载
  • 作者:Peter Wallbridge ; Selina M. Parry ; Sourav Das
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:15274
  • DOI:10.1038/s41598-018-33666-7
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:% predicted (r = -0.32). CT-measured lateral intercostal mass correlate negatively with parasternal ultrasound intercostal thickness. These data confirm ultrasound of parasternal intercostal musculature is reproducible. Lower intercostal muscle quantity and quality reflects greater COPD spirometric severity. This novel tool may have biomarker potential for both the systemic effects of COPD on muscle as well as local disruption of respiratory mechanics. The negative correlation between CT and ultrasound measurements may reflect complex site-dependent interactions between respiratory muscles and the chest wall.
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