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  • 标题:A new pharmacokinetic model for 90Y-ibritumomab tiuxetan based on 3-dimensional dosimetry
  • 本地全文:下载
  • 作者:F. Morschhauser ; B. Dekyndt ; C. Baillet
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:14860
  • DOI:10.1038/s41598-018-33160-0
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:In-IT in blood (AUC) and Mean Residence Time (MRT) that have not been reported so far for IT. Finally, the elimination process appears to occur in a compartment other than the liver or the spleen and suggests the metabolism of mAbs may take place mainly on the vascular compartment level.
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