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文章基本信息

  • 标题:Comprehensive analysis of the tumor immune micro-environment in non-small cell lung cancer for efficacy of checkpoint inhibitor
  • 本地全文:下载
  • 作者:Jeong-Sun Seo ; Ahreum Kim ; Jong-Yeon Shin
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:14576
  • DOI:10.1038/s41598-018-32855-8
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:T cell activation is decreased by the abundance of B cells and macrophages in immune-competent subtypes. Therefore, identifying immune subtypes in lung cancer and their impact on tumor micro-environment will lead to clinical tools for assessing LUADs and LUSCs in patients, as well as maximize the efficacy of immune checkpoint inhibitors.
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