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  • 标题:Neprilysin inhibition promotes corneal wound healing
  • 本地全文:下载
  • 作者:Rachel M. Genova ; Kacie J. Meyer ; Michael G. Anderson
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:14385
  • DOI:10.1038/s41598-018-32773-9
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:mice compared to WT controls 3 days after injury. Daily intraperitoneal administration of the NEP inhibitor thiorphan also accelerated corneal wound healing after alkali injury in WT mice. Collectively, our data identify a previously unknown role of NEP in the cornea, in which pharmacologic inhibition of its activity may provide a novel therapeutic option for patients with corneal injury.
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