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  • 标题:Pleomorphic xanthoastrocytomas of adults: MRI features, molecular markers, and clinical outcomes
  • 本地全文:下载
  • 作者:Jing Yan ; Jingliang Cheng ; Furong Liu
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:14275
  • DOI:10.1038/s41598-018-32273-w
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:mutation was found in 12 of 29 patients. In 36 patients with isocitrate dehydrogenases 1 and 2 (IDH1/2) data, only one had IDH1 mutation and no patient had IDH2 mutation. Anaplastic features were common (24/50) and significantly associated with high rates of recurrence or progression (P < 0.001). In conclusion, this study expands our knowledge on the MRI features, molecular markers, and clinical outcomes of adult PXAs, to some extent different from pediatric PXAs.
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