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  • 标题:MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer
  • 本地全文:下载
  • 作者:Mustafa Kahraman ; Anne Röske ; Thomas Laufer
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:11584
  • DOI:10.1038/s41598-018-29917-2
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:). Our results also suggest that changes in miRNA expression during NCT may have predictive potential to predict pathological complete response (pCR). In conclusion we report that miRNA expression measured from blood facilitates early and minimally-invasive diagnosis of basal-like TNBC. We also demonstrate that NCT has a significant influence on miRNA expression. Finally, we show that blood-borne miRNA profiles monitored over time have potential to predict pCR.
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