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  • 标题:Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering
  • 本地全文:下载
  • 作者:Ingy I. Abdallah ; Ronald van Merkerk ; Esmée Klumpenaar
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:9961
  • DOI:10.1038/s41598-018-28177-4
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:by 5 times. This variant can be used to enhance amorphadiene production and in turn artemisinin biosynthesis. Our findings provide the basis for the first step in improving industrial production of artemisinin and they open up possibilities for further engineering and understanding of ADS.
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