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  • 标题:HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles
  • 本地全文:下载
  • 作者:Deokcheol Lee ; Noboru Taniguchi ; Katsuaki Sato
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:9601
  • DOI:10.1038/s41598-018-28023-7
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:cells were generated in the muscle belly of rat supraspinatus muscles after rotator cuff transection, and some of these cells expressed PDGFRA in intra-muscular spaces. Thus, our findings suggest that the enhance expression of HMGB2 induces the adipogenesis of MSCs and the fat infiltration into skeletal muscles through the cascade of HMGB2-PDGFRA.
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