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  • 标题:Genomic analysis of a Raoultella ornithinolytica strain causing prosthetic joint infection in an immunocompetent patient
  • 本地全文:下载
  • 作者:Mamadou Beye ; Issam Hasni ; Piseth Seng
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:9462
  • DOI:10.1038/s41598-018-27833-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:We sequenced the genome of Raoultella ornithinolytica strain Marseille-P1025 that caused a rare case of prosthetic joint infection in a 67-year-old immunocompetent male. The 6.7-Mb genome exhibited a genomic island (RoGI) that was unique among R. ornithinolytica strains. RoGI was likely acquired by lateral gene transfer from a member of the Pectobacterium genus and coded for a type IVa secretion system found in other pathogenic bacteria and that may have conferred strain Marseille-P1025 an increased virulence. Strain Marseille-P1025 was also able to infect, multiply within, and kill Acanthamoaeba castellanii amoebae.
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