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  • 标题:Detection of genetic cardiac diseases by Ca2+ transient profiles using machine learning methods
  • 本地全文:下载
  • 作者:Martti Juhola ; Henry Joutsijoki ; Kirsi Penttinen
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:9355
  • DOI:10.1038/s41598-018-27695-5
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:transients are disease-specific. By including healthy controls in the classifications, the best classification accuracy obtained was still high: approximately 79%. In conclusion, we demonstrate as the proof of principle that the computational machine learning methodology appears to be a powerful means to accurately categorize iPSC-CMs and could provide effective methods for diagnostic purposes in the future.
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