文章基本信息
- 标题：Blockade of HMGB1 Attenuates Diabetic Nephropathy in Mice
- 本地全文：下载
- 作者：Xiaochen Chen ; Jin Ma ; Tony Kwan 等
- 期刊名称：Scientific Reports
- 电子版ISSN：2045-2322
- 出版年度：2018
- 卷号：8
- 期号：1
- 页码：8319
- DOI：10.1038/s41598-018-26637-5
- 语种：English
- 出版社：Springer Nature
- 摘要：diabetic mice, suggesting the protection provided by esRAGE was primarily through interruption of RAGE and TLR4 pathways. We conclude that strategies to block the interaction between HMGB1 and its receptors may be effective in preventing the development of DN.
