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  • 标题:Insight into the fission mechanism by quantitative characterization of Drp1 protein distribution in the living cell
  • 本地全文:下载
  • 作者:Bernadeta Maria Michalska ; Karina Kwapiszewska ; Joanna Szczepanowska
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:8122
  • DOI:10.1038/s41598-018-26578-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:of 31 ± 10 nM. We estimated the average number of Drp1 molecules forming the functional fission complex to be approximately 100, representing not more than 14% of all Drp1 oligomers. We showed that the upregulated fission induced by niclosamide is accompanied by an increase in the number of large Drp1 oligomers.
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