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  • 标题:Hematopoietic Stem Cells as a Novel Source of Dental Tissue Cells
  • 本地全文:下载
  • 作者:Katie R. Wilson ; In-Hong Kang ; Uday Baliga
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:8026
  • DOI:10.1038/s41598-018-26258-y
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:cells within dental tissues of recipient mice, which also stained for markers of cell populations in pulp, PDL and AvB (used above), indicating that transplanted HSCs can differentiate into cells in dental tissues. These hematopoietic-derived cells deposited collagen and can differentiate in osteogenic media, indicating that they are functional. Thus, our studies demonstrate, for the first time, that cells in pulp, PDL and AvB can have a hematopoietic origin, thereby opening new avenues of therapy for dental diseases and injuries.
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