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  • 标题:Electrochemical detection of NGF using a reduced graphene oxide- titanium nitride nanocomposite
  • 本地全文:下载
  • 作者:Zheng Wei ; Yanchun Wang ; Junping Zhang
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:6929
  • DOI:10.1038/s41598-018-25196-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 μM with a detection limit of 2.6 nM.
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