文章基本信息

标题：Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APPNL-F/NL-F knock-in mice
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作者：Disha Shah ; Amira Latif-Hernandez ; Bart De Strooper 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：6264
DOI：10.1038/s41598-018-24657-9
语种：English
出版社：Springer Nature
摘要：mice demonstrates that cognitive flexibility and synchronicity of telencephalic activity are specifically altered by early Aβ pathology without changes in APP neurochemistry.