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  • 标题:Transverse dielectrophoretic-based DNA nanoscale confinement
  • 本地全文:下载
  • 作者:Sara Mahshid ; Jia Lu ; Abrar A. Abidi
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:5981
  • DOI:10.1038/s41598-018-24132-5
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:) between the top and bottom electrodes, a DEP field gradient is established and used to concentrate, confine and linearly extend DNA in nanogrooves as small as 100-nm in width. We also demonstrate reversible loading/unloading of DNA molecules into nanogrooves and nanopits by switching frequency (between 10 kHz to 100 kHz). The technology presented in this paper provides a new method for single-molecule trapping and analysis.
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