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  • 标题:Evaluation and optimization of differentiation conditions for human primary brown adipocytes
  • 本地全文:下载
  • 作者:XingYun Wang ; LiangHui You ; XianWei Cui
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:5304
  • DOI:10.1038/s41598-018-23700-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:-receptor agonist sensitivity. As an important element of culture medium, triiodothyronine was found to be essential for differentiation and metabolic property maintenance. Furthermore, compared with other reported methods, this protocol induced a specific intrinsic differentiation program. Our study provides not only an optimized method for human BAC differentiation but also a cell model with good differentiation and thermogenic capacity for brown adipose research.
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