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  • 标题:Tolerance of chronic HDACi treatment for neurological, visceral and lung Niemann-Pick Type C disease in mice
  • 本地全文:下载
  • 作者:Md. Suhail Alam ; Bruce Cooper ; Joseph D. Farris
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:3875
  • DOI:10.1038/s41598-018-22162-7
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:mice, with no injury. Together, these data support feasibility of tolerable, chronic administration of an HDACi formulation that treats murine NPC neurological disease and lung pathology, a frequent cause of death in this and possibly additional disorders.
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